Efficacy and safety of high-dose influenza vaccine in elderly adults: A systematic review and meta-analysis. Seasonal influenza vaccination in adults. Centers for Disease Control and Prevention. Fluzone high-dose seasonal influenza vaccine.Soreness, pain or color change at the site of the shot.In a large study comparing high-dose and standard-dose flu vaccines, people who received the high-dose vaccine were more likely to develop side effects during the week after getting the vaccine. Similar to other flu vaccines, the high-dose flu vaccine is updated every year to protect against the flu strains most likely to cause the flu during the upcoming flu season. So if you are approved to get a high-dose flu vaccine but it isn't available, get the flu vaccine that is available.
Studies also have found higher antibody levels in older adults who received high-dose flu vaccines than in those who received standard-dose flu vaccines.īut any flu vaccination is better than none. Looking at previous flu seasons, researchers found that among people age 65 and older, high-dose flu vaccines generally help prevent flu-related hospital stays better than the standard-dose flu vaccines do. Rates for hospital stays and death linked to flu are generally higher in this age group than they are for younger people. People age 65 and older are generally at higher risk than others for severe flu and complications. Why is it needed?įlu data collected by the CDC shows that standard-dose flu vaccines likely don't work as well in people over age 65 as they do in younger populations. But it boosts the immune response by including an ingredient called an adjuvant. One flu vaccine recommended for older adults has the same amount of antigen as the standard dose vaccine. Some high-dose flu vaccines include 3 to 4 times as much flu virus antigen - the part of the vaccine that stimulates the immune system - as standard flu vaccines.
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